Yves Pommier Selected Research

A-Form DNA (A-DNA)

1/2020	Topoisomerase I-driven repair of UV-induced damage in NER-deficient cells.
2/2015	Microtubule-targeting agents augment the toxicity of DNA-damaging agents by disrupting intracellular trafficking of DNA repair proteins.
1/2005	Proteomic identification of heat shock protein 90 as a candidate target for p53 mutation reactivation by PRIMA-1 in breast cancer cells.

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Yves Pommier Research Topics

Disease

200	Neoplasms (Cancer) 03/2024 - 01/2002
27	Breast Neoplasms (Breast Cancer) 01/2024 - 01/2003
19	Genomic Instability 01/2022 - 09/2007
19	Carcinoma (Carcinomatosis) 01/2018 - 10/2002
19	Poisoning 11/2016 - 07/2002
17	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 03/2024 - 09/2011
16	Ataxia Telangiectasia (Louis Bar Syndrome) 03/2024 - 05/2003
15	Leukemia 10/2021 - 08/2002
11	Acquired Immunodeficiency Syndrome (AIDS) 07/2018 - 12/2002
10	Lung Neoplasms (Lung Cancer) 02/2024 - 08/2002
10	Hypersensitivity (Allergy) 01/2021 - 10/2006
8	Infections 01/2016 - 01/2009
7	Colorectal Neoplasms (Colorectal Cancer) 01/2024 - 05/2004
7	Glioblastoma (Glioblastoma Multiforme) 01/2023 - 02/2008
6	Lymphoma (Lymphomas) 01/2021 - 12/2003
6	Colonic Neoplasms (Colon Cancer) 03/2016 - 03/2002
5	Prostatic Neoplasms (Prostate Cancer) 01/2022 - 12/2007
5	HIV Infections (HIV Infection) 01/2016 - 03/2005
4	Hypoxia (Hypoxemia) 01/2021 - 02/2004
4	Ovarian Neoplasms (Ovarian Cancer) 01/2020 - 09/2012
4	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 01/2010
4	Bloom Syndrome 01/2017 - 10/2005
4	Ewing Sarcoma (Sarcoma, Ewing) 09/2015 - 07/2009
3	Brain Neoplasms (Brain Tumor) 01/2023 - 11/2003
3	Bites and Stings (Sting) 01/2023 - 01/2020
3	Fanconi Anemia (Fanconi's Anemia) 01/2023 - 11/2012
3	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 10/2021 - 04/2011
3	Mitochondrial Diseases (Mitochondrial Disease) 09/2014 - 09/2004
3	Visceral Leishmaniasis (Kala Azar) 10/2012 - 12/2007
3	Sarcoma (Soft Tissue Sarcoma) 02/2011 - 07/2002

Drug/Important Bio-Agent (IBA)

69	DNA (Deoxyribonucleic Acid)IBA 10/2023 - 04/2003
56	Type I DNA Topoisomerases (Topoisomerase I)IBA 01/2023 - 01/2002
46	CamptothecinIBA 01/2023 - 02/2002
38	Proteins (Proteins, Gene)FDA Link 10/2023 - 12/2002
26	Topotecan (Hycamtin)FDA LinkGeneric 03/2024 - 08/2002
20	Poly(ADP-ribose) Polymerase InhibitorsIBA 03/2024 - 09/2010
20	Irinotecan (Camptosar)FDA LinkGeneric 03/2024 - 08/2002
18	Topoisomerase I InhibitorsIBA 01/2023 - 03/2002
17	EnzymesIBA 01/2022 - 05/2003
16	Cisplatin (Platino)FDA LinkGeneric 03/2024 - 09/2002
16	Antineoplastic Agents (Antineoplastics)IBA 10/2022 - 01/2003
16	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 01/2021 - 02/2002
15	Biomarkers (Surrogate Marker)IBA 02/2022 - 06/2005
14	NSC 724998IBA 01/2023 - 11/2007
13	tyrosyl-DNA phosphodiesteraseIBA 10/2021 - 12/2006
12	PlatinumIBA 10/2023 - 01/2016
11	Phosphotransferases (Kinase)IBA 03/2024 - 10/2002
10	Etoposide (VP 16)FDA LinkGeneric 03/2024 - 11/2003
10	PoisonsIBA 01/2023 - 02/2004
10	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 01/2003
9	olaparibIBA 02/2024 - 02/2014
9	Messenger RNA (mRNA)IBA 01/2024 - 12/2002
9	Topoisomerase InhibitorsIBA 03/2023 - 01/2010
8	talazoparibIBA 03/2024 - 02/2014
7	Human immunodeficiency virus 1 p31 integrase proteinIBA 07/2018 - 10/2011
7	IntegrasesIBA 01/2016 - 03/2006
7	TrabectedinIBA 03/2014 - 07/2002
6	berzosertibIBA 03/2024 - 12/2014
6	Transcription Factors (Transcription Factor)IBA 01/2024 - 07/2004
6	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2023 - 09/2010
6	Mitochondrial DNA (mtDNA)IBA 01/2023 - 09/2013
6	indimitecanIBA 01/2020 - 12/2012
6	Histones (Histone)IBA 01/2019 - 06/2005
5	Histone Deacetylase InhibitorsIBA 01/2023 - 11/2003
5	Carboplatin (JM8)FDA LinkGeneric 01/2023 - 01/2016
5	rucaparibIBA 01/2023 - 02/2014
5	ChromatinIBA 01/2022 - 11/2009
5	Type II DNA Topoisomerases (Topoisomerase II)IBA 01/2021 - 08/2002
5	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 01/2014 - 12/2008
5	Raltegravir Potassium FDA Link 12/2012 - 01/2009
4	Immunoconjugates (Immunoconjugate)IBA 01/2023 - 11/2019
4	Drug CombinationsIBA 01/2023 - 06/2004
4	niraparibIBA 01/2023 - 01/2018
4	veliparibIBA 01/2023 - 09/2011
4	Hormones (Hormone)IBA 01/2022 - 01/2006
4	Gemcitabine FDA Link 01/2021 - 08/2002
4	Paclitaxel (Taxol)FDA LinkGeneric 01/2021 - 01/2003
4	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2021 - 04/2003
4	Temozolomide (Temodar)FDA LinkGeneric 01/2020 - 09/2015
4	Mitoxantrone (Novantrone)FDA LinkGeneric 01/2020 - 12/2007
4	aminoflavoneIBA 01/2017 - 06/2005
4	Small Interfering RNA (siRNA)IBA 03/2014 - 09/2007
3	PM 01183IBA 03/2024 - 01/2023
3	Cytotoxins (Cytolysins)IBA 03/2024 - 01/2008
3	LigandsIBA 03/2023 - 01/2009
3	UbiquitinIBA 01/2023 - 08/2008
3	InterferonsIBA 01/2023 - 10/2021
3	RNA (Ribonucleic Acid)IBA 01/2022 - 12/2010
3	A-Form DNA (A-DNA)IBA 01/2020 - 01/2005
3	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 12/2019 - 12/2004
3	Hydroxyurea (Hydrea)FDA LinkGeneric 01/2019 - 09/2007
3	NucleosidesIBA 01/2019 - 01/2014
3	RNA Helicases (RNA Helicase)IBA 01/2018 - 09/2012
3	LactamsIBA 01/2017 - 05/2007
3	EWS-FLI fusion proteinIBA 09/2015 - 02/2011
3	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2014 - 09/2004
3	Checkpoint Kinase 2IBA 12/2011 - 01/2009
3	DNA-Activated Protein KinaseIBA 12/2009 - 05/2003

Therapy/Procedure

51	Therapeutics 10/2023 - 08/2002
25	Drug Therapy (Chemotherapy) 02/2024 - 07/2002